The team isolated activation-tagged mutant lines in which expression of a rice NAS gene, OsNAS3, was increased by introducing 35S enhancer elements. The OsNAS3 activation-tagged plant seeds, which accumulated more iron and zinc, were fed to anemic mice to test for bioavailability and mice recovered to have a normal hemoglobin level within two weeks. This research result is anticipated to help widespread dietary problem of mineral deficiency.
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